SAPEA provides scientific advice for policy within the context of the Scientific Advice Mechanism (SAM) of the European Commission. This document sets out the SAPEA guidelines on advising policymakers and society, as well as internal procedures for quality assurance of scientific advice. The aim is to assure the excellence and independence of SAPEA’s policy advice through the provision of clear guidelines. Scientific advice for policy provided by SAPEA will be done in the form of evidence review reports. The procedures described in this document are a first version and might be revised in due time.