ALLEA‘s Framework Programme 9 Working Group calls for the EU to set itself and meet the ambition of being the world leader in research and innovation in the development and realisation of the next Framework Programme. That Framework Programme‘s agitating concern should be to support research and innovation originality and creativity, and not to be led by administrative capacities. This will require a significant resource commitment especially for Horizon 2020‘s most successful initiatives such as the European Research Council and the Marie Skłodowska-Curie Actions. As importantly, however, the EU must add value, not replicate, national research systems, and put in place the foundations for a programme that incentivises interdisciplinarity, mobility, internationalism, excellence, impact focused on European societies not just economic or industrial benefit, and impact for the long-term.